VCFROC(1)

💖 VCFROC(1) — vcfroc, from the vcflib crew 💖

okay bestie, welcome to vcfroc, a manual page from section 1. it's giving statistics, it's giving ROC curves, it's giving "let me check how good your variant calls actually are." let's get into it 🦋

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✨ NAME ✨

vcfroc — that's the whole name, that's the whole vibe 💅

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🌸 SYNOPSIS 🌸

vcfroc options []

yep, that's it. you hand it options, it does the thing. no cap ✨

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🎀 DESCRIPTION 🎀

so basically? vcfroc generates a pseudo-ROC curve using sensitivity and specificity estimated against a putative truth set. 🫶

and the thresholding? that's provided by successive QUAL cutoffs. like, it slides through QUAL values one after another and re-scores each time. main character energy fr fr 👑

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💅 OPTIONS 💅

the options, babes:

• -t, --truth-vcf FILE — use this VCF as ground truth for ROC generation. this is the truth set, the moment, the standard you're being judged against 😭
• -w, --window-size N — compare records up to this many bp away. default is 30. so like, if two records are chillin' within that distance, they get compared 🌈
• -c, --complex — directly compare complex alleles, and don't parse into primitives. no decomposing, no breaking things down, just straight-up comparison 🔥
• -r, --reference FILE — the FASTA reference file. you know, the reference. the blueprint. the source material 📖✨

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⭐ EXIT VALUES ⭐

• 0 — Success 🎉 slay, it worked
• not 0 — Failure 💀 it did not work

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🌈 SEE ALSO 🌈

• vcflib(1) — the whole fam, go say hi 🫶

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🧚 OTHER 🧚

👑 LICENSE

Copyright 2011-2024 (C) Erik Garrison and vcflib contributors. MIT licensed. Copyright 2020-2024 (C) Pjotr Prins.

🍓 AUTHORS

Erik Garrison and vcflib contributors. icons, honestly 🎀

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real talk: this is vcfroc from vcflib, and that's the whole page. go build a pseudo-ROC curve, bestie, i'm obsessed 💜

vcfroc (vcflib) — that's the sign-off, mwah 💋