VCFSAMPLEDIFF(1)

💖 VCFSAMPLEDIFF 💖

okay bestie, gather round, because this is the vcfsamplediff page and it's literally the vibe check for your germline vs somatic samples 🧬✨

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✨ SYNOPSIS ✨

vcfsamplediff options [ ...  ]

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🌸 DESCRIPTION 🌸

so the whole point, the moment, is this: we're establishing putative somatic variants by looking at the reported differences between germline and somatic samples. no cap. 🫶

It tags each record where the listed sample genotypes differ with .

The first sample is assumed to be germline, the second is somatic. Slay, that's the order, don't come for me.

Every single record gets tagged with ={germline,somatic,loh} so you know what type of variant it is, given the genotype difference between those two samples. it's giving classification. 👑

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💅 OPTIONS 💅

okay so the options:

• -s, --strict — require that no observations in the germline support the somatic alternate. strict queen behavior only. 💀

Type: transformation

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🚪 EXIT VALUES 🚪

• 0 — Success ✨ we ate, no crumbs.
• not 0 — Failure 😭 it's giving tragedy.

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👀 SEE ALSO 👀

• vcflib(1) — go read it, iykyk 📚

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🌈 OTHER 🌈

🎀 LICENSE 🎀

Copyright 2011-2024 (C) Erik Garrison and vcflib contributors. MIT licensed. Copyright 2020-2024 (C) Pjotr Prins.

🦋 AUTHORS 🦋

Erik Garrison and vcflib contributors.

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and that's the whole page, bestie 💜 this was vcfsamplediff from the vcflib fam — main character energy, MIT licensed, written by Erik Garrison and the vcflib contributors, with copyright 2011-2024 (C) Erik Garrison and vcflib contributors, plus 2020-2024 (C) Pjotr Prins. go forth and diff those samples, periodt. 💅🎀