TMSCORE(1)

πŸ’– NAME πŸ’–

okay so TMSCORE(1) lives in the General Commands Manual 🌸 and it's all about TM-score, an algorithm that figures out how similar the topologies of two protein structures are 🧚

πŸŽ€ VERSION πŸŽ€

This documentation is for the TM-score version released on 2011/01/30 πŸ“… so keep that date in mind, bestie ⏰

✨ SYNOPSIS ✨

Three ways to slay this program πŸ’…

  1. Compare model and native:
TMscore model native
  1. Set your own d0, like 5 Angstroms:
TMscore model native -d 5
  1. Write a superposition file called TM.sup and check it out in Rasmol πŸ¦‹:
TMscore model native -o TM.sup
rasmol -script TM.sup

🌈 DESCRIPTION 🌈

So this program compares two protein structures and hunts down the best superposition, the one with the highest TM-score πŸ‘‘. Your input structures have to be in the PDB format πŸ“„, no exceptions. By default, the TM-score gets normalized by the second protein πŸ’œ. If you're lost, just run the program with no arguments and it'll give you a quick brief πŸ™ˆ.


πŸ¦‹ OPTIONS πŸ¦‹

  • -o filename.sup β€” spits the superposition out into the file you name, and it's ready to go in rasmol 🌸
  • -d value β€” sets d0 to the number of angstroms you give it ✨

πŸ”— SEE ALSO πŸ”—

Check out TMalign and rasmol 🧚

When you're using this program and want the deeper details, go read the publication in NucleicAcidsRes. Specifically, NucleicAcidsRes. (2005) Volume 33 page 2303ff. by Zhang and Skolnick πŸ“š iykyk.

πŸ‘‘ AUTHOR πŸ‘‘

For comments or suggestions, email zhng@umich.edu πŸ’Œ

This manpage was compiled by Tim Booth (tbooth@ceh.ac.uk) 🫢


Okay that's the tea, bestie πŸ’… This page was last updated on 2011-02-03, and TMSCORE(1) is still iconic 😭✨