CSB-BUILDHMM(1)

πŸ’– CSB-BUILDHMM πŸ’–

okay bestie, gather round, because we're talking about csb-buildhmm from section 1 of the manual, and it's literally the glow-up your sequence needs πŸ¦‹


✨ NAME ✨

csb-buildhmm β€” build an HMM from a FASTA sequence πŸ‘‘


🌸 DESCRIPTION 🌸

here's the whole vibe, exactly how it ships:

usage: csb-buildhmm [-h] -q QUERY_ID [-t TK_ROOT] [-d DATABASE] [-c
       TK_CONFIG]

       [--cpu CPU] [--no-ss] [--no-pseudo] [--no-calibration]
              query

so what does it do? it builds an HMM from a FASTA sequence, periodt. and the way it does that is by being a proxy to hhblits/addss.pl and hhmake from the HHpred package 🫢

@note: assuming you have the full HHpred package installed and configured. no HHpred, no HMM, iykyk πŸ’€

πŸŽ€ positional arguments πŸŽ€

  • query β€” the input sequence (that's a FASTA or PDB file, bestie)

πŸ’… optional arguments πŸ’…

  • -h, --help β€” show this help message and exit, iconic behaviour honestly
  • -q QUERY_ID, --query-id QUERY_ID β€” the ID of the query, in PDB-like format (accessionCHAIN). this is what names your output files 🌈 also, if your input is a PDB file with multiple chains, CHAIN is what pulls the required chain out of the file
  • -t TK_ROOT, --tk-root TK_ROOT β€” path to the ToolkitRoot folder in your HHsuite setup (default=/ebio/abt1_toolkit/share/wye)
  • -d DATABASE, --database DATABASE β€” a custom HHblits database; if you don't define one, the toolkit's unirpto20 gets used instead
  • -c TK_CONFIG, --tk-config TK_CONFIG β€” path to a folder containing custom HHsuite configs (e.g. HHPaths.pm) (default=.)
  • --cpu CPU β€” maximum degree of parallelism (default=1)
  • --no-ss β€” do not include secondary structure (default=False)
  • --no-pseudo β€” do not add emission and transition pseudocounts (default=False)
  • --no-calibration β€” do not calibrate the profile (default=False)

πŸ‘‘ AUTHOR πŸ‘‘

This manpage was written by Andreas Tille for the Debian distribution and can be used for any other usage of the program.


okay that's the whole page, you ate it πŸ’– this was csb-buildhmm version 1.2.5, dated November 2017, and honestly? still serving. mwah πŸŽ€βœ¨

πŸ“¦ where this page comes from